Julius_Seizeher said:
Aside from the unfortunate effects described by Crissco, I'm pretty sure juicing often causes sudden heart failure too.
Not worth it.
How do you define "sudden heart failure"? If you mean "fulminant" myocarditis (inflammation of the heart muscle) deteriorating to acute heart failure... the answer is not really. Typically "sudden heart failure" and the preceding myocarditis can often occur due to an infectious agent, such as some kinda virus. A new study however, does seem to show that AAS use does affect LV EF (left ventricle ejection fraction) in long term AAS users:
http://www.theheart.org/article/1071741.do
Baggish AL, Weiner RB, Kanayama G, et al. Long term anabolic-androgenic steroid use is associated with left ventricular dysfunction. Circ Heart Fail 2010; DOI:10.1161/CIRCHEARTFAILURE.109.931063
A normal/health EF is typically around 65-70%. EF refers to the percentage/fraction of blood present in the left ventricle at the end of diastole that gets ejected into the systemic circulation by the action of the ventricle. Acceptable EF is pretty much anything > 55%. This article seems to suggest that EF is compromised w/ long term AAS use, probably due to morphological LV changes associated with these drugs. Having a lower EF means that AAS users will have a lower physiological reserve should they get into trouble with an MI (heart attack) or something like that.
If you mean sudden cardiac death (SCD), yes, anabolics can increase the risk of sudden cardiac death, but there are tons of other risk factors. Typically, sudden cardiac death is mitigated when one goes into a VF (ventricular fibrillation) and there is basically no blood getting ejected into the systemic circuit. A VF is a malignant heart rhythm that usually stems from an event where blood flow to a certain part of the heart's electrochemical conduction machinery is compromised. This results in messed up electrically signaling and thus the heart doesn't beat properly. There is also increased risk of VF in heart failure patients, as pathological changes to LV structure can make pt's more prone to VFs.
There are, however, multiple factors that affect risk of SCD, including family history, pervious MIs, CAD (coronary artery disease), having an EF < 45%, a "bad" lipid profile, global inflammation status as indicated by CRP (C-reactive protein), diabetes, drug use, etc. AAS use can increase risk of CAD, poor lipid profile, and EF as mentioned earlier. If you scan the literature, you'll find mostly case reports on SCD in AAS users... but no real definitive meta-analysis. Case reports, I think, are the "lowest form of life" when it comes to scientific studies, as they just basically tell a story and don't do a whole lot more.
My point with all this is, yes AAS use can definitely increase risk of adverse cardiovascular events. However, prudent/conservative use and appropriate surveillance of lipids, liver enzymes, eating a clean diet, and doing cardio can help to curb the risk and help to thwart any potential adverse events before the proverbial shiiite hits the fan. It all boils down to the cost-benefit analysis by the user/potential user.