The prospect of work the next morning before 9 AM can often hang negatively over a first date drinks date on a Tuesday or Wednesday night.
the biggest difference between college and the white collar working world is the consequences of messing up. In college, if you mess up, the absolute worst consequence is that you fail a specific class and have to take it again. Knowing that's the worst consequence is liberating and you can have a more carefree mentality going into dates. In the white collar working world, if you fucck up at work, you can get fired. When you get fired, you're likely facing 3-9 months of job interviews while getting a fraction of your former salary from state unemployment payments. That's going to affect quality of life in a major way. You can't have as carefree of a mentality on your weeknight dates.