UPDATE:
Had to modify my plans after wearing it 2 weeks straight for 10-12 hours a day.
On the 14th day my body felt like it had been run over by a truck, my heart rate was 10-12 bpm elevated overnight and I had trouble sleeping. Classic overtraining/stress reactions by the body. So I have decided to go either a 2 on/2 off or 2 on/1 off split depending on how my body feels by the end of the week this week.
I believe this is because I had a heavier vest at 30lbs when for my bodyweight, a 20lb vest would have been recommended.
So I will say do not underestimate that component. It's not the weight on any one day that is the issue, it's the constant weight being carried around day after day while you are doing everything that ends up catching up to you. I'd recommend a vest around 10-12% of your bodyweight so it would be easier to wear longer.
That being said, it appears my body put on muscle while losing fat because my weight stayed stable but my waist size dropped, I look leaner and my veins in my arms are just looking very spidery now.
Estimated tape measure average has me in the mid 12s now where I was in the low 14s prior.