Despite me being under 21 and thus having denial of access to nightclubs here in Las Vegas, I can offer a few suggestions since I know quite a bit about the lifestyle.
First off, and this is pretty inevitible, you need connections. I know of people who can get into clubs without being carded and without being charged cover, all because of connections. If they can do those things with connections, then having connections can go a long way in hooking up with shot girls.
Secondly, observe how people hit on these women, and how they get burned down. The key to attracting a girl that get a lot of male attention is to stand out from the crowd. Show her that you are not intimidated, and be sure to use neg-hits a lot. Shot girls get a lot of compliments, so it will come as a suprise to them if you neg-hit them. Stand out, and do things differently than the many other guys that try to get a lay with them.
That is pretty much all I can say. This is difficult, but with right technique it can be as easy as picking up an average chick.