It all depends, what kind of goals are you going for, want to bulk and gain weight, and size, then do warmup sets, like a weight that is easy to do for 10, a couple of those then do a 2 sets of 10, 2 sets of 8, and 2 sets of 6. If your going for strength and trying to tighten, tone the muscle for strength and power, do 2 sets of 5, 2 sets of 3, and a set of 2 and a set of 1. But a method I use, is have 3 different bench workouts, 50 reps over 5 sets, 25 reps over 5 sets, or 12 reps over 5 sets, space them however you want, but make suer that the last rep of each set is hard, and you can barely get it up on the last one. Just alternate each one of those routines to get a all around workout. But mix in some dumbell flies, incline and stuff too after that, and especially triceps.