If you make it with intent it's fine.
If you stand across the room and stare and her, make eye contact, and do that ALL night w/o approaching, or stare for a few hours then approach, it might be deemed a little creepy.
In passing if you make eye contact smile, say hi. Great way to show confidence.
And when you are talking to ANYONE. Make firm eye contact, it shows power, confidence and respect.
Being someone in the "business world" it kills me when i'm talking to someone one on one and they stare at the wall or their shoes and something thats not me.
Same goes for you, if you are talking to a girl you are approaching and you glance in her eyes then look down quickly, or you are staring at something else, this shows insecurity. A DJ or PUA or..any man for that matter is always confident, and eye contact is a confident trait.