The PUA concepts do work at some level, but the truth is no one can turn you into something that you are NOT, unless you work on yourself.
I just finished Wayne's book... really it's Dr. Love with sex, so it's okay. But I found Wayne's book a bit long winded with some tedious examples from his own life. He pretty much follows the formula of many in this business... He claims he used to be a complete idiot with women, and now he isn't.
I would stay away from PUA stuff. Read "The System", by Doc Love, an oldie but a goody, it reads fast, is funny, and pretty much defines what women really respond to, filled with great advice like 'If a woman says ANYTHING except yes, then the answer is no, and the man should move on.'
Then read "Book of Pook", brilliant stuff.
Work on yourself, get in shape, be happy with yourself, learn to walk away from women that are not interested in you. Develop confidence, and exhibit self control, but yourself first and everything will work out for you in the end.